Symbol
Name
ID

Thbd
thrombomodulin
MGI:98736

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Vasculitis	Stroke	Pulmonary embolism
Disease(s) Associated with THBD	Vasculitis	Stroke	Pulmonary embolism
cerebral infarction
rheumatoid arthritis
thrombophilia due to thrombomodulin defect

Mouse Phenotypes

abnormal heart development

abnormal heart morphology

abnormal endocardium morphology

increased heart weight

enlarged heart

increased heart right ventricle weight

cardiac fibrosis

hemothorax

lung hemorrhage

gastrointestinal hemorrhage

intracerebral hemorrhage

liver hemorrhage

skin hemorrhage

pulmonary hypertension

increased myocardial infarct size

Availability

Mouse Genotype

Thbd^tm1Rdr/Thbd^tm1Rdr

Thbd^tm1Wlr/Thbd^tm1Wlr

Thbd^tm2.1Emc/Thbd^tm2.1Emc

Thbd^tm1Wlr/Thbd^tm2Rdr

Tg(Tek-cre)1Ywa/0
Thbd^tm2Rdr/Thbd^tm2Wlr (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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